Transgenic A(1 )adenosine receptor overexpression increases myocardial resistance to ischemia

Activation of myocardial A(1) adenosine receptors (A(1)AR) protects the heart from ischemic injury. In this study transgenic mice were created using the cardiac-specific α-myosin heavy chain promoter and rat A(1)AR cDNA. Heart membranes from two transgene positive lines displayed ≈1,000-fold overexp...

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Détails bibliographiques
Auteurs principaux: Matherne, G. Paul, Linden, Joel, Byford, Anne M., Gauthier, Naomi S., Headrick, John P.
Format: Artigo
Langue:Inglês
Publié: The National Academy of Sciences of the USA 1997
Sujets:
Biological Sciences
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC21086/
https://ncbi.nlm.nih.gov/pubmed/9177254
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