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Transgenic A(1 )adenosine receptor overexpression increases myocardial resistance to ischemia
Activation of myocardial A(1) adenosine receptors (A(1)AR) protects the heart from ischemic injury. In this study transgenic mice were created using the cardiac-specific α-myosin heavy chain promoter and rat A(1)AR cDNA. Heart membranes from two transgene positive lines displayed ≈1,000-fold overexp...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
The National Academy of Sciences of the USA
1997
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC21086/ https://ncbi.nlm.nih.gov/pubmed/9177254 |
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