In vivo blockade of OX40 ligand inhibits thymic stromal lymphopoietin driven atopic inflammation

Thymic stromal lymphopoietin (TSLP) potently induces deregulation of Th2 responses, a hallmark feature of allergic inflammatory diseases such as asthma, atopic dermatitis, and allergic rhinitis. However, direct downstream in vivo mediators in the TSLP-induced atopic immune cascade have not been iden...

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Detalhes bibliográficos
Main Authors: Seshasayee, Dhaya, Lee, Wyne P., Zhou, Meijuan, Shu, Jean, Suto, Eric, Zhang, Juan, Diehl, Laurie, Austin, Cary D., Meng, Y. Gloria, Tan, Martha, Bullens, Sherron L., Seeber, Stefan, Fuentes, Maria E., Labrijn, Aran F., Graus, Yvo M.F., Miller, Lisa A., Schelegle, Edward S., Hyde, Dallas M., Wu, Lawren C., Hymowitz, Sarah G., Martin, Flavius
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2007
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2096422/
https://ncbi.nlm.nih.gov/pubmed/18060034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI33559
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