Dual B Cell Immunotherapy Is Superior to Individual Anti-CD20 Depletion or BAFF Blockade in Murine Models of Spontaneous or Accelerated Lupus

OBJECTIVE: To determine whether a combination of B cell depletion and BAFF blockade is more effective than monotherapy in treating models of spontaneous or accelerated systemic lupus erythematosus (SLE) in (NZB × NZW)F1 mice. METHODS: Clinical parameters such as disease progression–free survival, pr...

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Detalhes bibliográficos
Publicado no:Arthritis Rheumatol
Main Authors: Lin, WeiYu, Seshasayee, Dhaya, Lee, Wyne P, Caplazi, Patrick, McVay, Sami, Suto, Eric, Nguyen, Allen, Lin, Zhonghua, Sun, Yonglian, DeForge, Laura, Balazs, Mercedesz, Martin, Flavius, Zarrin, Ali A
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2015
Assuntos:
Systemic Lupus Erythematosus
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4312898/
https://ncbi.nlm.nih.gov/pubmed/25303150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.38907
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