Tumor Spectrum, Tumor Latency and Tumor Incidence of the Pten-Deficient Mice

BACKGROUND: Pten functionally acts as a tumor suppressor gene. Lately, tissue-specific ablation of Pten gene in mice has elucidated the role of Pten in different tumor progression models. However, a temporally controlled Pten loss in all adult tissues to examine susceptibility of various tissues to...

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Bibliographic Details
Main Authors: Lu, Tsai-Ling, Chang, Junn-Liang, Liang, Chih-Chia, You, Li-Ru, Chen, Chun-Ming
Format: Artigo
Language:Inglês
Published: Public Library of Science 2007
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2077932/
https://ncbi.nlm.nih.gov/pubmed/18043744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0001237
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