Transgenic mice exhibiting inducible and spontaneous Cre activities driven by a bovine keratin 5 promoter that can be used for the conditional analysis of basal epithelial cells in multiple organs

BACKGROUND: Cre/loxP-mediated genetic modification is the most widely used conditional genetic approach used in the mouse. Engineered Cre and the mutated ligand-binding domain of estrogen receptor fusion recombinase (CreER(T)) allow temporal control of Cre activity. RESULTS: In this study, we have g...

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Detalhes bibliográficos
Main Authors: Liang, Chih-Chia, You, Li-Ru, Chang, Junn-Liang, Tsai, Ting-Fen, Chen, Chun-Ming
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2009
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2653515/
https://ncbi.nlm.nih.gov/pubmed/19272176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1423-0127-16-2
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