Distribution of neocarzinostatin conjugated to biotinylated chimeric monoclonal antibody Fab fragments after administration of avidin.

We have developed chimeric Fab fragments of MAb A7 (chA7Fab) and have reported on their potential usefulness as a carrier of neocarzinostatin (NCS). However, a large amount of chA7Fab accumulates in the kidneys which might cause renal failure. This was one of the major side-effects of the chA7Fab-NC...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Otsuji, E., Yamaguchi, T., Matsumura, H., Yamamoto, K., Tsuruta, H., Yata, Y., Nishi, H., Okamoto, K., Kitamura, K., Takahashi, T.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group 1996
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2074675/
https://ncbi.nlm.nih.gov/pubmed/8761376
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