Effects of neocarzinostatin-chimeric Fab conjugates on the growth of human pancreatic carcinoma xenografts.

Neocarzinostatin (NCS) was bound covalently to human/mouse chimeric Fab fragments of MAb A7 (chA7Fab) directed against human pancreatic carcinoma. The anti-tumour effect of chA7Fab-NCS was tested in a nude mouse model on pancreatic carcinoma and compared with A7-NCS or NCS alone. The anti-tumour eff...

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Autors principals: Otsuji, E., Yamaguchi, T., Tsuruta, H., Yata, Y., Nishi, H., Okamoto, K., Taniguchi, K., Kato, M., Kotani, T., Kitamura, K., Takahashi, T.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 1996
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2074529/
https://ncbi.nlm.nih.gov/pubmed/8630275
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