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Production, Binding and Cytotoxicity of Human/Mouse Chimeric Monoclonal Antibody‐Neocarzinostatin Conjugate
A human/mouse chimeric Fab monoclonal antibody A7 (chFabA7) was covalently coupled to neocarzinostatin (NCS) by the SPDP method at various chFabA7:NCS substitution ratios. The antigen‐binding activity of the conjugate, examined by ELISA using fixed antigen‐positive colon cancer cells, was identical...
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| Udgivet i: | Jpn J Cancer Res |
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| Main Authors: | , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Blackwell Publishing Ltd
1993
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5919093/ https://ncbi.nlm.nih.gov/pubmed/8276723 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.1993.tb02820.x |
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