Efficacy and Specificity of a Monoclonal Antibody‐Drug Conjugate in Chemotherapy by Intratumoral Injection

The murine monoclonal antibody (Mab) A7 conjugated to neocarzinostatin (A7‐NCS) was injected intratumorally (IT) into tumor bearing nude mice. Its pharmacokinetics and tumoricidal effects were compared in the high, moderate and low antigen expressing xenograft for SW1116, WiDr and KB tumor‐bearing n...

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Detaylı Bibliyografya
Yayımlandı:Jpn J Cancer Res
Asıl Yazarlar: Kitamura, Kazuya, Takahashi, Toshio, Miyagaki, Takuya, Yamaoka, Nobuki, Tsurumi, Hiroshi, Ohtsuji, Eigo, Kamiguchi, Michiko, Noguchi, Akinori, Yamaguchi, Toshiharu
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Blackwell Publishing Ltd 1992
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5918930/
https://ncbi.nlm.nih.gov/pubmed/1387634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.1992.tb01978.x
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