Efficacy and Specificity of a Monoclonal Antibody‐Drug Conjugate in Chemotherapy by Intratumoral Injection

The murine monoclonal antibody (Mab) A7 conjugated to neocarzinostatin (A7‐NCS) was injected intratumorally (IT) into tumor bearing nude mice. Its pharmacokinetics and tumoricidal effects were compared in the high, moderate and low antigen expressing xenograft for SW1116, WiDr and KB tumor‐bearing n...

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發表在:Jpn J Cancer Res
Main Authors: Kitamura, Kazuya, Takahashi, Toshio, Miyagaki, Takuya, Yamaoka, Nobuki, Tsurumi, Hiroshi, Ohtsuji, Eigo, Kamiguchi, Michiko, Noguchi, Akinori, Yamaguchi, Toshiharu
格式: Artigo
語言:Inglês
出版: Blackwell Publishing Ltd 1992
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5918930/
https://ncbi.nlm.nih.gov/pubmed/1387634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.1992.tb01978.x
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