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The major human and mouse granzymes are structurally and functionally divergent
Approximately 2% of mammalian genes encode proteases. Comparative genomics reveals that those involved in immunity and reproduction show the most interspecies diversity and evidence of positive selection during evolution. This is particularly true of granzymes, the cytotoxic proteases of natural kil...
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| Autors principals: | , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
The Rockefeller University Press
2006
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2064598/ https://ncbi.nlm.nih.gov/pubmed/17116752 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200606073 |
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