G protein–independent Ras/PI3K/F-actin circuit regulates basic cell motility

Phosphoinositide 3-kinase (PI3K)γ and Dictyostelium PI3K are activated via G protein–coupled receptors through binding to the Gβγ subunit and Ras. However, the mechanistic role(s) of Gβγ and Ras in PI3K activation remains elusive. Furthermore, the dynamics and function of PI3K activation in the abse...

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Bibliografische gegevens
Hoofdauteurs: Sasaki, Atsuo T., Janetopoulos, Chris, Lee, Susan, Charest, Pascale G., Takeda, Kosuke, Sundheimer, Lauren W., Meili, Ruedi, Devreotes, Peter N., Firtel, Richard A.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The Rockefeller University Press 2007
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Research Articles
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2064438/
https://ncbi.nlm.nih.gov/pubmed/17635933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200611138
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