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The regulation of cell motility and chemotaxis by phospholipid signaling

Phosphoinositide 3-kinase (PI3K), PTEN and localized phosphatidylinositol (3,4,5)-trisphosphate [PtdIns(3,4,5)P(3)] play key roles in chemotaxis, regulating cell motility by controlling the actin cytoskeleton in Dictyostelium and mammalian cells. PtdIns(3,4,5)P(3), produced by PI3K, acts via diverse...

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Bibliografiske detaljer
Main Authors: Kölsch, Verena, Charest, Pascale G., Firtel, Richard A.
Format: Artigo
Sprog:Inglês
Udgivet: 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2671295/
https://ncbi.nlm.nih.gov/pubmed/18287584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.023333
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