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Spatio-temporal Regulation of Ras Activity Provides Directional Sensing

Cells' ability to detect and orient themselves in chemoattractant gradients has been the subject of numerous studies, but the underlying molecular mechanisms remain largely unknown [1]. Ras activation is the earliest polarized response to chemoattractant gradients downstream from heterotrimeric...

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Detalhes bibliográficos
Main Authors: Zhang, Sheng, Charest, Pascale G., Firtel, Richard A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2590931/
https://ncbi.nlm.nih.gov/pubmed/18948008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2008.08.069
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