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A Ras signaling complex controls the RasC-TORC2 pathway and directed cell migration

Ras was found to regulate Dictyostelium chemotaxis, but the mechanisms that spatially and temporally control Ras activity during chemotaxis remain largely unknown. We report the discovery of a Ras signaling complex that includes the Ras guanine exchange factor (RasGEF) Aimless, RasGEFH, protein phos...

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Detalhes bibliográficos
Main Authors: Charest, Pascale G., Shen, Zhouxin, Lakoduk, Ashley, Sasaki, Atsuo T., Briggs, Steven P., Firtel, Richard A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2893887/
https://ncbi.nlm.nih.gov/pubmed/20493808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2010.03.017
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