Activation-dependent substrate recruitment by the eukaryotic translation initiation factor 2 kinase PERK

Regulated phosphorylation of the α subunit of eukaryotic translation initiation factor 2 (eIF2α) by the endoplasmic reticulum (ER) stress-activated protein kinase PERK modulates protein synthesis and couples the production of ER client proteins with the organelle's capacity to fold and process...

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Bibliographic Details
Main Authors: Marciniak, Stefan J., Garcia-Bonilla, Lidia, Hu, Junjie, Harding, Heather P., Ron, David
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 2006
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Research Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2063550/
https://ncbi.nlm.nih.gov/pubmed/16418533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200508099
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