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Activation-dependent substrate recruitment by the eukaryotic translation initiation factor 2 kinase PERK
Regulated phosphorylation of the α subunit of eukaryotic translation initiation factor 2 (eIF2α) by the endoplasmic reticulum (ER) stress-activated protein kinase PERK modulates protein synthesis and couples the production of ER client proteins with the organelle's capacity to fold and process...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
The Rockefeller University Press
2006
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2063550/ https://ncbi.nlm.nih.gov/pubmed/16418533 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200508099 |
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