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Perk-Dependent Translational Regulation Promotes Tumor Cell Adaptation and Angiogenesis in Response to Hypoxic Stress

It has been well established that the tumor microenvironment can promote tumor cell adaptation and survival. However, the mechanisms that influence malignant progression have not been clearly elucidated. We have previously demonstrated that cells cultured under hypoxic/anoxic conditions and transfor...

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Detalhes bibliográficos
Main Authors: Blais, Jaime D., Addison, Christina L., Edge, Robert, Falls, Theresa, Zhao, Huijun, Wary, Kishore, Koumenis, Costas, Harding, Heather P., Ron, David, Holcik, Martin, Bell, John C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1698539/
https://ncbi.nlm.nih.gov/pubmed/17030613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01145-06
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