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Perk-Dependent Translational Regulation Promotes Tumor Cell Adaptation and Angiogenesis in Response to Hypoxic Stress

It has been well established that the tumor microenvironment can promote tumor cell adaptation and survival. However, the mechanisms that influence malignant progression have not been clearly elucidated. We have previously demonstrated that cells cultured under hypoxic/anoxic conditions and transfor...

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Autors principals: Blais, Jaime D., Addison, Christina L., Edge, Robert, Falls, Theresa, Zhao, Huijun, Wary, Kishore, Koumenis, Costas, Harding, Heather P., Ron, David, Holcik, Martin, Bell, John C.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2006
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1698539/
https://ncbi.nlm.nih.gov/pubmed/17030613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01145-06
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