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Potent inhibition of tau fibrillization with a multivalent ligand

Small-molecule inhibitors of tau fibrillization are under investigation as tools for interrogating the tau aggregation pathway and as potential therapeutic agents for Alzheimer’s disease. Established inhibitors include thiacarbocyanine dyes, which can inhibit recombinant tau fibrillization in the pr...

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Detalles Bibliográficos
Main Authors: Honson, Nicolette S., Jensen, Jordan R., Darby, Michael V., Kuret, Jeff
Formato: Artigo
Idioma:Inglês
Publicado: 2007
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2048976/
https://ncbi.nlm.nih.gov/pubmed/17854770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2007.08.166
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