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Potent inhibition of tau fibrillization with a multivalent ligand
Small-molecule inhibitors of tau fibrillization are under investigation as tools for interrogating the tau aggregation pathway and as potential therapeutic agents for Alzheimer’s disease. Established inhibitors include thiacarbocyanine dyes, which can inhibit recombinant tau fibrillization in the pr...
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| Главные авторы: | , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2007
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2048976/ https://ncbi.nlm.nih.gov/pubmed/17854770 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2007.08.166 |
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