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Ca(2+)/calmodulin kinase II increases ryanodine binding and Ca(2+)-induced sarcoplasmic reticulum Ca(2+) release kinetics during β-adrenergic stimulation
We aimed to define the relative contribution of both PKA and Ca(2+)/calmodulin-dependent protein kinase II (CaMKII) cascades to the phosphorylation of RyR2 and the activity of the channel during β-adrenergic receptor (βAR) stimulation. Rat hearts were perfused with increasing concentrations of the β...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2045504/ https://ncbi.nlm.nih.gov/pubmed/17643448 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2007.05.022 |
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