Ca(2+)/calmodulin kinase II increases ryanodine binding and Ca(2+)-induced sarcoplasmic reticulum Ca(2+) release kinetics during β-adrenergic stimulation

We aimed to define the relative contribution of both PKA and Ca(2+)/calmodulin-dependent protein kinase II (CaMKII) cascades to the phosphorylation of RyR2 and the activity of the channel during β-adrenergic receptor (βAR) stimulation. Rat hearts were perfused with increasing concentrations of the β...

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Main Authors: Ferrero, Paola, Said, Matilde, Sánchez, Gina, Vittone, Leticia, Valverde, Carlos, Donoso, Paulina, Mattiazzi, Alicia, Mundiña-Weilenmann, Cecilia
Formato: Artigo
Idioma:Inglês
Publicado: 2007
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2045504/
https://ncbi.nlm.nih.gov/pubmed/17643448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2007.05.022
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