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Mechanism of Calmodulin Inhibition of Cardiac Sarcoplasmic Reticulum Ca(2+) Release Channel (Ryanodine Receptor)

The functional effects of calmodulin (CaM) on single cardiac sarcoplasmic reticulum Ca(2+) release channels (ryanodine receptors) (RyR2s) were determined in the presence of two endogenous channel effectors, MgATP and reduced glutathione, using the planar lipid bilayer method. Single-channel activiti...

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Autors principals: Xu, Le, Meissner, Gerhard
Format: Artigo
Idioma:Inglês
Publicat: Biophysical Society 2004
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1303927/
https://ncbi.nlm.nih.gov/pubmed/14747315
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