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Early effects of Epac depend on the fine-tuning of the sarcoplasmic reticulum Ca(2+) handling in cardiomyocytes

In cardiac muscle, signaling through cAMP governs many fundamental cellular functions, including contractility, relaxation and automatism. cAMP cascade leads to the activation of the classic protein kinase A but also to the stimulation of the recently discovered exchange protein directly activated b...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:J Mol Cell Cardiol
Main Authors: Lezcano, N., Mariángelo, JIE., Vittone, L., Wehrens, XHT., Said, M., Mundiña-Weilenmann, C.
Format: Artigo
Jezik:Inglês
Izdano: 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5801154/
https://ncbi.nlm.nih.gov/pubmed/29037982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2017.10.005
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