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Early effects of Epac depend on the fine-tuning of the sarcoplasmic reticulum Ca(2+) handling in cardiomyocytes
In cardiac muscle, signaling through cAMP governs many fundamental cellular functions, including contractility, relaxation and automatism. cAMP cascade leads to the activation of the classic protein kinase A but also to the stimulation of the recently discovered exchange protein directly activated b...
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| Publicado no: | J Mol Cell Cardiol |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5801154/ https://ncbi.nlm.nih.gov/pubmed/29037982 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2017.10.005 |
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