Calcium Dobesilate (CaD) Attenuates High Glucose and High Lipid-Induced Impairment of Sarcoplasmic Reticulum Calcium Handling in Cardiomyocytes

Calcium dobesilate (CaD) is used effectively in patients with diabetic microvascular disorder, retinopathy, and nephropathy. Here we sought to determine whether it has an effect on cardiomyocytes calcium mishandling that is characteristic of diabetic cardiomyopathy. Cardiomyocytes were sterile isola...

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Vydáno v:Front Cardiovasc Med
Hlavní autoři: Deng, Jianxin, Cai, Xiangsheng, Hao, Mingyu, Liu, Xueting, Chen, Zelong, Li, Haiyan, Liu, Junying, Liao, Yunxiu, Fu, Hao, Chen, Huiyan, Qin, Gangjian, Yan, Dewen
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2021
Témata:
Cardiovascular Medicine
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7884338/
https://ncbi.nlm.nih.gov/pubmed/33604360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcvm.2021.637021
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