Calcium Dobesilate (CaD) Attenuates High Glucose and High Lipid-Induced Impairment of Sarcoplasmic Reticulum Calcium Handling in Cardiomyocytes

Calcium dobesilate (CaD) is used effectively in patients with diabetic microvascular disorder, retinopathy, and nephropathy. Here we sought to determine whether it has an effect on cardiomyocytes calcium mishandling that is characteristic of diabetic cardiomyopathy. Cardiomyocytes were sterile isola...

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Enregistré dans:
Détails bibliographiques
Publié dans:Front Cardiovasc Med
Auteurs principaux: Deng, Jianxin, Cai, Xiangsheng, Hao, Mingyu, Liu, Xueting, Chen, Zelong, Li, Haiyan, Liu, Junying, Liao, Yunxiu, Fu, Hao, Chen, Huiyan, Qin, Gangjian, Yan, Dewen
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2021
Sujets:
Cardiovascular Medicine
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7884338/
https://ncbi.nlm.nih.gov/pubmed/33604360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcvm.2021.637021
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