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Transient Ca(2+) depletion of the sarcoplasmic reticulum at the onset of reperfusion

AIMS: Myocardial stunning is a contractile dysfunction that occurs after a brief ischaemic insult. Substantial evidence supports that this dysfunction is triggered by Ca(2+) overload during reperfusion. The aim of the present manuscript is to define the origin of this Ca(2+) increase in the intact h...

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Bibliographic Details
Main Authors: Valverde, Carlos A., Kornyeyev, Dmytro, Ferreiro, Marcela, Petrosky, Azadé D., Mattiazzi, Alicia, Escobar, Ariel L.
Format: Artigo
Language:Inglês
Published: Oxford University Press 2010
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2819836/
https://ncbi.nlm.nih.gov/pubmed/19920131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvp371
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