Replication of Poliovirus Requires Binding of the Poly(rC) Binding Protein to the Cloverleaf as Well as to the Adjacent C-Rich Spacer Sequence between the Cloverleaf and the Internal Ribosomal Entry Site

The 5′ nontranslated region of poliovirus RNA contains two highly structured regions, the cloverleaf (CL) and the internal ribosomal entry site (IRES). A cellular protein, the poly(rC) binding protein (PCBP), has been reported to interact with the CL either alone or in combination with viral protein...

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Main Authors: Toyoda, Hidemi, Franco, David, Fujita, Kentaro, Paul, Aniko V., Wimmer, Eckard
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2007
Assuntos:
Genome Replication and Regulation of Viral Gene Expression
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2045387/
https://ncbi.nlm.nih.gov/pubmed/17609276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00516-07
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