Genetic Analysis of a Poliovirus/Hepatitis C Virus (HCV) Chimera: Interaction between the Poliovirus Cloverleaf and a Sequence in the HCV 5′ Nontranslated Region Results in a Replication Phenotype

Internal ribosomal entry sites (IRESs) can function in foreign viral genomes or in artificial dicistronic mRNAs. We describe an interaction between the wild-type hepatitis C virus (HCV)-specific sequence and the poliovirus (PV) 5′-terminal cloverleaf in a PV/HCV chimeric virus (containing the HCV IR...

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Hlavní autoři: Zhao, Wei Dong, Lahser, Frederick C., Wimmer, Eckard
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2000
Témata:
Replication
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC112126/
https://ncbi.nlm.nih.gov/pubmed/10846111
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