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Genetic Analysis of a Poliovirus/Hepatitis C Virus (HCV) Chimera: Interaction between the Poliovirus Cloverleaf and a Sequence in the HCV 5′ Nontranslated Region Results in a Replication Phenotype

Internal ribosomal entry sites (IRESs) can function in foreign viral genomes or in artificial dicistronic mRNAs. We describe an interaction between the wild-type hepatitis C virus (HCV)-specific sequence and the poliovirus (PV) 5′-terminal cloverleaf in a PV/HCV chimeric virus (containing the HCV IR...

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Udgivet i:J Virol
Principais autores: Zhao, Wei Dong, Lahser, Frederick C., Wimmer, Eckard
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2000
Fag:
Replication
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC112126/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10846111/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.74.13.6223-6226.2000
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