Replication of Poliovirus Requires Binding of the Poly(rC) Binding Protein to the Cloverleaf as Well as to the Adjacent C-Rich Spacer Sequence between the Cloverleaf and the Internal Ribosomal Entry Site

The 5′ nontranslated region of poliovirus RNA contains two highly structured regions, the cloverleaf (CL) and the internal ribosomal entry site (IRES). A cellular protein, the poly(rC) binding protein (PCBP), has been reported to interact with the CL either alone or in combination with viral protein...

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Detalhes bibliográficos
Main Authors: Toyoda, Hidemi, Franco, David, Fujita, Kentaro, Paul, Aniko V., Wimmer, Eckard
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2007
Assuntos:
Genome Replication and Regulation of Viral Gene Expression
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2045387/
https://ncbi.nlm.nih.gov/pubmed/17609276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00516-07
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