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Replication of Poliovirus Requires Binding of the Poly(rC) Binding Protein to the Cloverleaf as Well as to the Adjacent C-Rich Spacer Sequence between the Cloverleaf and the Internal Ribosomal Entry Site

The 5′ nontranslated region of poliovirus RNA contains two highly structured regions, the cloverleaf (CL) and the internal ribosomal entry site (IRES). A cellular protein, the poly(rC) binding protein (PCBP), has been reported to interact with the CL either alone or in combination with viral protein...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Toyoda, Hidemi, Franco, David, Fujita, Kentaro, Paul, Aniko V., Wimmer, Eckard
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2007
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2045387/
https://ncbi.nlm.nih.gov/pubmed/17609276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00516-07
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