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Poly(rC) Binding Proteins and the 5′ Cloverleaf of Uncapped Poliovirus mRNA Function during De Novo Assembly of Polysomes
Poliovirus (PV) mRNA is unusual because it possesses a 5′-terminal monophosphate rather than a 5′-terminal cap. Uncapped mRNAs are typically degraded by the 5′ exonuclease XRN1. A 5′-terminal cloverleaf RNA structure interacts with poly(rC) binding proteins (PCBPs) to protect uncapped PV mRNA from 5...
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| Auteurs principaux: | , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society for Microbiology (ASM)
2008
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2395131/ https://ncbi.nlm.nih.gov/pubmed/18400854 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01513-07 |
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