From estrogen to androgen receptor: A new pathway for sex hormones in prostate

While all three coactivators ARA(70), steroid receptor coactivator 1, and RAC3/ACTR can enhance androgen receptor (AR) transcriptional activity at 1 nM dihydrotestosterone, we here demonstrate that only ARA(70) can induce AR transcriptional activity >30-fold in the presence of 10 nM 17β-estradiol...

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Bibliographic Details
Main Authors: Yeh, Shuyuan, Miyamoto, Hiroshi, Shima, Hiroki, Chang, Chawnshang
Format: Artigo
Language:Inglês
Published: The National Academy of Sciences 1998
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC20411/
https://ncbi.nlm.nih.gov/pubmed/9576916
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