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Akt suppresses androgen-induced apoptosis by phosphorylating and inhibiting androgen receptor

Whereas several apoptosis-related proteins have been linked to the antiapoptotic effects of Akt serine–threonine kinase, the search continues to explain the Akt signaling role in promoting cell survival via antiapoptotic effects. Here, we demonstrate that Akt phosphorylates the androgen receptor (AR...

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Autori principali: Lin, Hui-Kuan, Yeh, Shuyuan, Kang, Hong-Yo, Chang, Chawnshang
Natura: Artigo
Lingua:Inglês
Pubblicazione: The National Academy of Sciences 2001
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC34646/
https://ncbi.nlm.nih.gov/pubmed/11404460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.121173298
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