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Akt suppresses androgen-induced apoptosis by phosphorylating and inhibiting androgen receptor

Whereas several apoptosis-related proteins have been linked to the antiapoptotic effects of Akt serine–threonine kinase, the search continues to explain the Akt signaling role in promoting cell survival via antiapoptotic effects. Here, we demonstrate that Akt phosphorylates the androgen receptor (AR...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Lin, Hui-Kuan, Yeh, Shuyuan, Kang, Hong-Yo, Chang, Chawnshang
Format: Artigo
Sprache:Inglês
Veröffentlicht: The National Academy of Sciences 2001
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC34646/
https://ncbi.nlm.nih.gov/pubmed/11404460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.121173298
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