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Promotion of agonist activity of antiandrogens by the androgen receptor coactivator, ARA70, in human prostate cancer DU145 cells

Although hormone therapy with antiandrogens has been widely used for the treatment of prostate cancer, some antiandrogens may act as androgen receptor (AR) agonists that may result in antiandrogen withdrawal syndrome. The molecular mechanism of this agonist response, however, remains unclear. Using...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Miyamoto, Hiroshi, Yeh, Shuyuan, Wilding, George, Chang, Chawnshang
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC22623/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9636157/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.13.7379
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