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Promotion of agonist activity of antiandrogens by the androgen receptor coactivator, ARA70, in human prostate cancer DU145 cells

Although hormone therapy with antiandrogens has been widely used for the treatment of prostate cancer, some antiandrogens may act as androgen receptor (AR) agonists that may result in antiandrogen withdrawal syndrome. The molecular mechanism of this agonist response, however, remains unclear. Using...

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Détails bibliographiques
Auteurs principaux: Miyamoto, Hiroshi, Yeh, Shuyuan, Wilding, George, Chang, Chawnshang
Format: Artigo
Langue:Inglês
Publié: The National Academy of Sciences 1998
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC22623/
https://ncbi.nlm.nih.gov/pubmed/9636157
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