Androgen receptor gene mutations in human prostate cancer.

We screened human prostate cancer tissues for the presence of somatic mutations in the hormone binding domain of the androgen receptor (AR) gene. Exons E-H were amplified from genomic DNA using the polymerase chain reaction and analyzed by denaturing gradient gel electrophoresis (DGGE), which separa...

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Detalhes bibliográficos
Main Authors: Newmark, J R, Hardy, D O, Tonb, D C, Carter, B S, Epstein, J I, Isaacs, W B, Brown, T R, Barrack, E R
Formato: Artigo
Idioma:Inglês
Publicado em: 1992
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC49492/
https://ncbi.nlm.nih.gov/pubmed/1631125
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