Androgen receptor gene mutations in human prostate cancer.

We screened human prostate cancer tissues for the presence of somatic mutations in the hormone binding domain of the androgen receptor (AR) gene. Exons E-H were amplified from genomic DNA using the polymerase chain reaction and analyzed by denaturing gradient gel electrophoresis (DGGE), which separa...

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Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Newmark, J R, Hardy, D O, Tonb, D C, Carter, B S, Epstein, J I, Isaacs, W B, Brown, T R, Barrack, E R
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 1992
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC49492/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1631125/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.14.6319
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Androgen receptor gene mutations in human prostate cancer.

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