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Androgen receptor gene mutations in human prostate cancer.

We screened human prostate cancer tissues for the presence of somatic mutations in the hormone binding domain of the androgen receptor (AR) gene. Exons E-H were amplified from genomic DNA using the polymerase chain reaction and analyzed by denaturing gradient gel electrophoresis (DGGE), which separa...

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Dades bibliogràfiques
Publicat a:Proc Natl Acad Sci U S A
Autors principals: Newmark, J R, Hardy, D O, Tonb, D C, Carter, B S, Epstein, J I, Isaacs, W B, Brown, T R, Barrack, E R
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 1992
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC49492/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1631125/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.14.6319
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