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Androgen receptor gene mutations in human prostate cancer.

We screened human prostate cancer tissues for the presence of somatic mutations in the hormone binding domain of the androgen receptor (AR) gene. Exons E-H were amplified from genomic DNA using the polymerase chain reaction and analyzed by denaturing gradient gel electrophoresis (DGGE), which separa...

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Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Newmark, J R, Hardy, D O, Tonb, D C, Carter, B S, Epstein, J I, Isaacs, W B, Brown, T R, Barrack, E R
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 1992
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC49492/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1631125/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.14.6319
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