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Δ(5)-Androstenediol is a natural hormone with androgenic activity in human prostate cancer cells

It is known that androst-5-ene-3β,17β-diol (Adiol), a precursor of testosterone (T), can activate estrogen target genes. The androgenic activity of Adiol itself, however, is poorly understood. Using a transient transfection assay, we here demonstrate in human prostate cancer cells that Adiol can act...

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Autori principali: Miyamoto, Hiroshi, Yeh, Shuyuan, Lardy, Henry, Messing, Edward, Chang, Chawnshang
Natura: Artigo
Lingua:Inglês
Pubblicazione: The National Academy of Sciences 1998
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC21599/
https://ncbi.nlm.nih.gov/pubmed/9736693
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