Δ(5)-Androstenediol is a natural hormone with androgenic activity in human prostate cancer cells

It is known that androst-5-ene-3β,17β-diol (Adiol), a precursor of testosterone (T), can activate estrogen target genes. The androgenic activity of Adiol itself, however, is poorly understood. Using a transient transfection assay, we here demonstrate in human prostate cancer cells that Adiol can act...

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izdano v:	Proc Natl Acad Sci U S A
Principais autores:	Miyamoto, Hiroshi, Yeh, Shuyuan, Lardy, Henry, Messing, Edward, Chang, Chawnshang
Format:	Artigo
Jezik:	Inglês
Izdano:	National Academy of Sciences 1998
Teme:	Biological Sciences
Online dostop:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC21599/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9736693/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.19.11083
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