Inactivation of androgen receptor coregulator ARA55 inhibits androgen receptor activity and agonist effect of antiandrogens in prostate cancer cells

Antiandrogens given to antagonize androgen receptor (AR) activity gradually lose their efficacy as antagonists and eventually function as agonists to promote (instead of block) AR-mediated growth of prostate cancer cells. The mechanisms of how antiandrogens acquire this agonist activity during hormo...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Rahman, Mujib M., Miyamoto, Hiroshi, Lardy, Henry, Chang, Chawnshang
Format: Artigo
Sprache:Inglês
Veröffentlicht: The National Academy of Sciences 2003
Schlagworte:
Biological Sciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC154309/
https://ncbi.nlm.nih.gov/pubmed/12700349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0530097100
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge