Suppression of Δ(5)-androstenediol-induced androgen receptor transactivation by selective steroids in human prostate cancer cells

Our earlier report suggested that androst-5-ene-3β,7β-diol (Δ(5)-androstenediol or Adiol) is a natural hormone with androgenic activity and that two potent antiandrogens, hydroxyflutamide (Eulexin) and bicalutamide (Casodex), fail to block completely the Adiol-induced androgen receptor (AR) transact...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Chang, Hong-Chiang, Miyamoto, Hiroshi, Marwah, Padma, Lardy, Henry, Yeh, Shuyuan, Huang, Ko-En, Chang, Chawnshang
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1999
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC18006/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10500149/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.20.11173
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