Suppression of Δ(5)-androstenediol-induced androgen receptor transactivation by selective steroids in human prostate cancer cells

Our earlier report suggested that androst-5-ene-3β,7β-diol (Δ(5)-androstenediol or Adiol) is a natural hormone with androgenic activity and that two potent antiandrogens, hydroxyflutamide (Eulexin) and bicalutamide (Casodex), fail to block completely the Adiol-induced androgen receptor (AR) transact...

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Bibliografiske detaljer
Main Authors: Chang, Hong-Chiang, Miyamoto, Hiroshi, Marwah, Padma, Lardy, Henry, Yeh, Shuyuan, Huang, Ko-En, Chang, Chawnshang
Format: Artigo
Sprog:Inglês
Udgivet: The National Academy of Sciences 1999
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC18006/
https://ncbi.nlm.nih.gov/pubmed/10500149
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