A NOVEL FUNCTION OF VCP (VALOSIN CONTAINING PROTEIN; P97) IN THE CONTROL OF N-GLYCOSYLATION OF PROTEINS IN THE ENDOPLASMIC RETICULUM

α chain of T-cell receptor (TCR) is a typical ERAD (ER-associated degradation) substrate degraded in the absence of other TCR subunits. Depletion of derlin1 fails to induce accumulation of αTCR despite inducing accumulation of α1-antitrypsin, another ERAD substrate. Furthermore, while depletion of V...

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Bibliografiske detaljer
Main Authors: Lass, Agnieszka, McConnell, Elizabeth, Nowis, Dominika, Mechref, Yehia, Kang, Pilsoo, Novotny, Milos V., Wójcik, Cezary
Format: Artigo
Sprog:Inglês
Udgivet: 2007
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2040342/
https://ncbi.nlm.nih.gov/pubmed/17493577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.abb.2007.04.010
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