Unconventional p97/VCP-Mediated Endoplasmic Reticulum-to-Endosome Trafficking of a Retroviral Protein

Mouse mammary tumor virus (MMTV) encodes a Rem precursor protein that specifies both regulatory and accessory functions. Rem is cleaved at the endoplasmic reticulum (ER) membrane into a functional N-terminal signal peptide (SP) and the C terminus (Rem-CT). Rem-CT lacks a membrane-spanning domain and...

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Bibliographic Details
Published in:J Virol
Main Authors: Xu, Wendy Kaichun, Gou, Yongqiang, Lozano, Mary M., Dudley, Jaquelin P.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2021
Subjects:
Virus-Cell Interactions
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8223958/
https://ncbi.nlm.nih.gov/pubmed/33952644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00531-21
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