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A NOVEL FUNCTION OF VCP (VALOSIN CONTAINING PROTEIN; P97) IN THE CONTROL OF N-GLYCOSYLATION OF PROTEINS IN THE ENDOPLASMIC RETICULUM
α chain of T-cell receptor (TCR) is a typical ERAD (ER-associated degradation) substrate degraded in the absence of other TCR subunits. Depletion of derlin1 fails to induce accumulation of αTCR despite inducing accumulation of α1-antitrypsin, another ERAD substrate. Furthermore, while depletion of V...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2040342/ https://ncbi.nlm.nih.gov/pubmed/17493577 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.abb.2007.04.010 |
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