Replication fork regression in vitro by the Werner syndrome protein (WRN): Holliday junction formation, the effect of leading arm structure and a potential role for WRN exonuclease activity

Eitemau Tebyg

• THE WERNER AND BLOOM SYNDROME PROTEINS HELP RESOLVE REPLICATION BLOCKAGE BY CONVERTING (REGRESSED) HOLLIDAY JUNCTIONS TO FUNCTIONAL REPLICATION FORKS
  gan: Machwe, Amrita, et al.
  Cyhoeddwyd: (2011)
• Length-dependent degradation of single-stranded 3' ends by the Werner syndrome protein (WRN): implications for spatial orientation and coordinated 3' to 5' movement of its ATPase/helicase and exonuclease domains
  gan: Machwe, Amrita, et al.
  Cyhoeddwyd: (2006)
• Strand exchange of telomeric DNA catalyzed by the Werner syndrome protein (WRN) is specifically stimulated by TRF2
  gan: Edwards, Deanna N., et al.
  Cyhoeddwyd: (2014)
• The Werner Syndrome Protein Binds Replication Fork and Holliday Junction DNAs as an Oligomer
  gan: Compton, Sarah A., et al.
  Cyhoeddwyd: (2008)
• Selective blockage of the 3′→5′ exonuclease activity of WRN protein by certain oxidative modifications and bulky lesions in DNA
  gan: Machwe, Amrita, et al.
  Cyhoeddwyd: (2000)