The Werner Syndrome Protein Binds Replication Fork and Holliday Junction DNAs as an Oligomer

Werner syndrome is an inherited disease displaying a premature aging phenotype. The gene mutated in Werner syndrome encodes both a 3′ → 5′ DNA helicase and a 3′ → 5′ DNA exonuclease. Both WRN helicase and exonuclease preferentially utilize DNA substrates containing alternate secondary structures. By...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Compton, Sarah A., Tolun, Gökhan, Kamath-Loeb, Ashwini S., Loeb, Lawrence A., Griffith, Jack D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2008
Assuntos:
DNA: Replication, Repair, Recombination, and Chromosome Dynamics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2528990/
https://ncbi.nlm.nih.gov/pubmed/18596042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M803370200
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados